生命科學部
| 2024 年 7 月 18 日
物理系
| 2024 年 6 月 6 日
海洋科學系
| 2024 年 5 月 16 日
生命科學部
| 2024 年 2 月 20 日
數學系
| 2024 年 2 月 2 日
The research team is led by Prof. Danny LEUNG, Associate Professor of the Division of Life Science and Director of the Center for Epigenomics Research at HKUST (left), and Prof. Liona POON, Chairperson of the Department of Obstetrics and Gynaecology at CUHK’s Faculty of Medicine.
The research team is led by Prof. Danny LEUNG, Associate Professor of the Division of Life Science and Director of the Center for Epigenomics Research at HKUST (left), and Prof. Liona POON, Chairperson of the Department of Obstetrics and Gynaecology at CUHK’s Faculty of Medicine.
生命科學
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研究揭示在懷孕期間感染2019冠狀病毒病如何對胎盤造成不良影響

香港科技大學(科大)和香港中文大學(中大)今日公佈重大研究突破,揭示感染2019冠狀病毒病 (COVID-19)或會導致妊娠晚期併發症。研究發現COVID-19會顯著改變胎盤的基因調控,為研發更好的治療方案提供潛在分子靶點,或減輕COVID-19對母體和胎兒健康所造成的負面影響。

Japanese black seabream, one of the fish species in the study
Japanese black seabream, one of the fish species in the study
海洋科學
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Deciphering Fish Species Interactions for Climate Change Insights

A team led by the Hong Kong University of Science and Technology (HKUST) has developed a technique to study how different fish species interact with each other in a coastal region, a breakthrough that helps explain the complex relationships among marine species and how global warming impacts fish populations. By analyzing minute traces of fish DNA from samples of seawater, the team combined the use of environmental DNA – known as eDNA – and advanced statistical analysis to not only detect the presence of fish species, but also reveal how the species interact with each other. 

Prof. Tom CHEUNG, the S H Ho Associate Professor of Life Science in the Division of Life Science at HKUST (right), and his research group member Zhang Wenxin (Mphil student) (left).
Prof. Tom CHEUNG, the S H Ho Associate Professor of Life Science in the Division of Life Science at HKUST (right), and his research group member Zhang Wenxin (Mphil student) (left).
生命科學
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科大研究人員發現蛋白新靶點 或有助治療衰老相關疾病

香港科技大學(科大)的研究團隊利用骨骼肌的成人幹細胞(或肌肉幹細胞)作為模型系統,發現一種關鍵蛋白,或能揭示如何逆轉衰老過程,並有助進一步推動研發針對衰老相關疾病和各種線粒體疾病的干預治療措施。

HKUST President Prof. Nancy IP (center, front row), Director of HKUST’s Big Data Institute Prof. CHEN Lei (second left, front row), HKUST Division of Life Science Research Professor Prof. Amy FU (first right, front row), Hong Kong Center for Neurodegenerative Diseases (HKCeND) Chief Scientific Officer Dr. Fanny IP (first left, front row) and the first author of the research paper Prof. Fred ZHOU Xiaopu (second right, front row) take a group photo with other members of the research team.
HKUST President Prof. Nancy IP (center, front row), Director of HKUST’s Big Data Institute Prof. CHEN Lei (second left, front row), HKUST Division of Life Science Research Professor Prof. Amy FU (first right, front row), Hong Kong Center for Neurodegenerative Diseases (HKCeND) Chief Scientific Officer Dr. Fanny IP (first left, front row) and the first author of the research paper Prof. Fred ZHOU Xiaopu (second right, front row) take a group photo with other members of the research team.
生命科學
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科大取得重大科研突破 首度利用人工智能為阿爾茲海默症作早期風險預測

香港科技大學(科大)領導的國際研究團隊最近開發了一套人工智能模型,利用遺傳信息,可在出現病徵之前預測罹患阿爾茲海默症的風險。這項突破性研究為使用深度學習方法來預測疾病風險和揭示其分子機制開闢了道路。這將革新阿爾茲海默症及其他常見疾病如心血管疾病的診斷、干預、治療和臨床研究。

The authors of the published paper are, from left to right: Trung Duc Nguyen, Minh Khoa Ngo, Tuan Anh Nguyen (group leader), Thuy Linh Nguyen, and Thi Nhu-Y Le.
The authors of the published paper are, from left to right: Trung Duc Nguyen, Minh Khoa Ngo, Tuan Anh Nguyen (group leader), Thuy Linh Nguyen, and Thi Nhu-Y Le.
生命科學
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香港科技大學研究人員研究miRNA生物起源 揭開長久以來非經典切割機制的謎團

爲了研究並徹底驗證新發現的非經典切割機制,香港科技大學(科大)研究團隊在生命科學部助理教授阮俊英(Tuan Anh Nguyen)教授的帶領下,采用了多種尖端技術,如miRNA測序、pri-miRNA結構分析以及大約26萬個pri-miRNA的高通量切割實驗。與經典機制不同的是,非經典機制不依賴於經典機制所需的幾個關鍵蛋白和RNA特徵序列。

The surface of a colloidal crystal develops another crystal whose thickness increases with temperature in a power law before reaching the crystal-crystal transition temperature.
The surface of a colloidal crystal develops another crystal whose thickness increases with temperature in a power law before reaching the crystal-crystal transition temperature.
物理學
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晶體表面在固-固轉變前就可變成另一種晶體

冰在零下攝氏幾度尚未達到零度熔點時,表面就已經熔化出一薄層水了,這種預熔化現像對滑冰和雪花生長很重要。類似地,液體往往在達到其凝固溫度前便於平坦的基底上結出一薄層晶體,即預凝固或預結晶。逼近相變(如熔化和結晶)溫度時,表面層的厚度通常會增加並發散。除了預熔化和預凝固外,是否存在類似相變前兆的表面層仍很少被探索。

A research team led by Prof. TONG Rongbiao, Associate Professor of the Department of Chemistry at HKUST (middle)
A research team led by Prof. TONG Rongbiao, Associate Professor of the Department of Chemistry at HKUST (middle)
化學
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科大研究人員開發出嶄新方法合成炭疽黴素 刷新全球最高產量紀錄 有助研發針對超級細菌的強效抗生素

香港科技大學(科大)的研究團隊開發出一種嶄新化學合成方法製造炭疽黴素(anthracimycin)和炭疽黴素B (anthracimycin B),產量較現有方法多63倍,刷新全球最高產量紀錄。此項突破性的發現將大大推動把炭疽黴素轉化為抗生素的發展,以對付由抗生素耐藥細菌甚至超級細菌引起的致命細菌感染。

(From right) Prof. Angela WU, Associate Professor of HKUST’s Division of Life Science and Department of Chemical and Biological Engineering, post-doctoral fellow Dr. Lei YU as well as co-author of the paper, TAM Sing Ting
(From right) Prof. Angela WU, Associate Professor of HKUST’s Division of Life Science and Department of Chemical and Biological Engineering, post-doctoral fellow Dr. Lei YU as well as co-author of the paper, TAM Sing Ting
生命科學
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科大突破性發現罕見腫瘤細胞「間諜」 揭示不為人知的癌細胞

香港科技大學(科大)研究人員研發了一種可為冷凍和新鮮細胞組織樣本同時進行單細胞DNA和RNA測序的新技術,更利用這方法識別出偽裝為正常細胞的罕見腦腫瘤細胞「間諜」。是次發現為一些最複雜和罕見腫瘤的研究帶來突破,並為未來的藥物靶標發現開闢新方向。

Dr. Thuy Linh NGUYEN (left), and Trung Duc NGUYEN (right) are the co-first authors of the paper.
Dr. Thuy Linh NGUYEN (left), and Trung Duc NGUYEN (right) are the co-first authors of the paper.
生命科學
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解構秀麗隱桿線蟲pri-miRNA加工複合體的分子機制

小分子核糖核酸(microRNAs,以下簡稱miRNAs)是一種在動物和人類基因調控中發揮重要作用的小型核糖核酸(RNA),一直令許多科學家為之著迷。在生物學和醫學中,一項非常重要的研究範疇就是miRNA如何控制和調節基因表達,因為科學界一般相信,這個課題對理解細胞突變有重大作用,對於治療癌症和其他與細胞突變有關的疾病,至為關鍵。

Extensive coral bleaching occurred across depths on the north shore of Moorea during the 2019 marine heatwave.  Photo credit: Peter J. Edmunds.
Extensive coral bleaching occurred across depths on the north shore of Moorea during the 2019 marine heatwave.  Photo credit: Peter J. Edmunds.
海洋科學
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隱藏深海的熱浪對珊瑚礁構成威脅

2019年四月至五月,位於南太平洋中部法屬坡利尼西亞莫雷阿島一帶的珊瑚礁經歷了長時間且嚴重的高溫白化。由於該年並非厄爾尼諾年份,一般並不會出現這種情況,因此本事件令全球海洋科學界百思不解。